Propofol

Propofol - for 2018 one of the medicines, most widespread in the world, for anesthesia. Medicine for short-term lulling to slip in surgery is combined with the anesthetizing substances. Substance of dairy color exists in the market near from the 1980th, is used worldwide. In competent hands — it is very convenient, efficient, "managed" medicine, anesthesiologists consider.

2019: The shortage of a propofol in Germany

On November 24, 2019 it became known that in Germany the shortage of a propofol is observed. Physicians very much appreciate it that it provides a reliable anesthesia without unpleasant effects for patients

Without propofol anesthesiologists of Germany could not carry out treatment up to standard, speaks the chief anesthesiologist of Germany Getz Geldner

The problem consists that there are two producers which practically for 100% supply the German market: pharmkontserna of Fresenius and B.Braun. At the second for November, 2019 problems with delivery as do not deliver it packaging for a propofol are observed.

the Situation is heated. If the producer is not able to deliver goods further, we will have a serious problem, especially at small clinics and private doctors. I know at least two colleagues who at the end of December will not be able to work further if nothing changes,

Propofol is not the only medicine which shortage is observed in Germany. According to the federal union of wholesale interruptions in deliveries about 250 prescription medicines arose pharmaceutical medicines, for November, 2019. There are not enough soothing, means for pressure decrease, antidepressants and stomach drug. The reason of shortage of medicines consists in what makes them less producers. There are such active ingredients which are produced only by one company.

I fly into a rage from the fact that we constantly face the same problem. To me absolutely all the same who is guilty of it. I want to treat the patients well. For this purpose I need about 10 irreplaceable medicines, and I very strongly want that I had them, summarizes Geldner[1]

2018: Inexplicable death in clinics of Moscow. Investigation of Roszdravnadzor

Anesthetic murderer, inept doctors or negligence of the producer? In June, 2018 it became known that experts of Roszdravnadzor will put the end to disputes around a propofol. The large party is withdrawn for check at the request of scientific clinical center of the Russian Railway. Physicians suspect that medicine caused dangerous reactions in patients. Scandal over anesthetic was warmed up by series of inexplicable death in the Moscow clinics of plastic surgery.

Endotoxicosis — failure of internals — and a lethal outcome. So simple plastic surgeries for healthy women ended. Natalia's friends cannot still recover. The high quality stockbroker, the prize-winner of tender of millionaire investors wanted to go after plastics at the sea.

"It was written on transaction which had to be in September. And here, and room was made here. And when the destiny gives the chance, think that it is the car happy. And this car conducts you in an underworld, to some hell" — Natalya's friend says.

One of versions — during transactions the critical quantity of the most dangerous bacteria got to an organism of patients. In June, 2018 it became known that Roszdravnadzor, in fact, prohibited one of medicines using which in clinics carried out anesthesia. Propofol. But it is not absolutely prohibition — a quarantine and selection of a certain batch of medicine^[2].

"Roszdravnadzor gives a task to carry out quality tests of the samples of this medicine which are selected from hospital based on the Moscow laboratory of Roszdravnadzor — explained in department. — Now medicine is moved on quarantine storage. The notification on need without delay to make the decision on further circulation in the Russian Federation of medicine is sent to representative office of Frezenius Kabi LLC (Fresenius Kabi Russia)".

"Medicine is intended for intravenous anesthesia, introduction to an anesthesia and a sedation in intensive therapy. This medicine is intended only for use by specialists, people who have preparation in the field of anesthesiology" — the manager of department of anesthesiology and resuscitation of hospital of Botkin Sergey Osipov emphasizes.

But hardly patients knew about it. And whether people can know all medicines? They trust doctors who for the sake of this trust studied in medical school. Whether it is guilty of these tragedies propofol — whether there was it genuine, not overdue or, maybe, comprised something dangerous — it will be found out by expertizes which will be carried out by Roszdravnadzor and producer.

2009: Michael Jackson dies of a propofol

It is that propofol from which overdose the American pop idol Michael Jackson died. In 2009 his personal doctor Conrad Murray made to him an injection of a propofol. Approximately in 2 hours Murray returned and saw the patient lying on a bed with widely open eyes and a mouth. The doctor tried to reanimate the singer, but attempts were not crowned with success. The doctor formally had no right to use propofol at home.

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