MOUTHS OF MIREA: A vaccine patch

2024: Product Announcement

In January 2024, it became known about the development in Russia of a patch for painless vaccination. The authors of the development were scientists from the Institute of Fine Chemical Technologies named after M.V. Lomonosov RTU MIREA.

As the press service of the institute told Izvestia, pyramids with microneedles no more than 0.6 mm high pass through the stratum corneum of the skin, but do not affect nerve endings. This principle of operation allows you to make vaccination painless and effective. This can have a particularly big impact on vaccination of children.

It became known about the development in Russia of a patch for painless vaccination

Microneedles, after the drug or composition has penetrated the skin, dissolve in a few minutes or hours. The patch is suitable for a wide range of vaccines, and for some it allows you to reduce the dosage of antigens.

In addition, the press service told about another development of the institute - oral films:

Small plates with the drug are placed in the oral cavity and begin to act quickly by dissolution and absorption. At the same time, they do not injure the gastric mucosa and do not affect the pancreas. This method of drug delivery is suitable for a whole range of drugs. The film does not require water washing. In addition, for some drugs, this form of release shows higher bioavailability than in traditional tablets that dissolve in the stomach or intestine.

Rector of RTU MIREA Stanislav Kuj noted that in the near future the development of the institute will become an integral part of the Russian pharmaceutical industry. According to the plans of the university, the next stage of research will be the scaling of development for industrial production.

In 2021, American scientists from Stanford University and the University of North Carolina created a patch with a vaccine using a 3D printer. It turned out that this method of delivering the vaccine to the body is more effective than usual - the resulting immune response from the vaccine was 10 times stronger than when introduced into the muscle of the hand using a needle.^[1]

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