Oxford (knee endoprosthesis)

History

2024: Product Announcement

In late November 2024, Zimmer Biomet introduced Oxford's cement-free partial knee endoprosthesis, which received pre-market regulatory approval.

In traditional partial knee replacement, surgeons use bone cement to fix the implant in place. The cement-free approach allows naturally growing bone tissue to secure the implant, which should provide longer-term fixation, the company says. The new Oxford prosthesis also allows for improved long-term implant survival and surgery efficiency compared to cement prostheses. Cement-free endoprostheses have already been successfully used in more than 300,000 procedures worldwide, proving the results of safety and efficacy assessments from the FDA research device exception (IDE) study and preclinical studies.

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zimmerbiomet.com

The Oxford cement-free prosthesis is equipped with a movable bearing that allows the prosthesis to move along with the femoral component throughout its range of motion. Thus, the prosthesis mimics the natural movement of the knee joint, providing a wider range of movement and a more natural sensation. It also provides a more stable fixation of the implant to the bone to improve the long-term survival of the implant. Zimmer Biomet also notes that the tibial and femoral components of the system are equipped with a titanium and hydroxyapatite coating that promotes bone ingrowth into the implant.

According to the developers, the new endoprosthesis retains the more natural anatomical characteristics of the joint with a less invasive approach, which provides better results. The company plans to launch a new implant in the United States in the first quarter of 2025.^[1]

Notes