| Developers: | Coherence Neuro |
| Date of the premiere of the system: | July 2025 |
| Branches: | Pharmaceuticals, Medicine, Healthcare |
Content |
History
2025: Product Announcement
A consortium of researchers led by Professor George Malliaras from the University of Cambridge has developed innovative bioelectronic implants to treat chronic migraine. The project was named SPARCLE. The devices are compact implantable battery-free electrical pulse generators capable of stimulating peripheral nerves. This became known at the end of July 2025.
According to EurekaMagazine, the SPARCLE project combines academic research and medical startup Coherence Neuro, founded by Cambridge graduates Dr. Ben Woodington and Dr. Elise Jenkins.
The full name of the project stands for "Small form factor implantable Pulse generAtoRs for Chronic and Lifestyle-related disease managEment." The development is aimed at creating solutions for the treatment of three specific conditions: chronic migraine, pancreatic adenocarcinoma and spinal cord injuries.
The technological breakthrough of the project is the use of conductive polymers to create flexible microelectrodes. Professor Malliaras' Bioelectronics Laboratory develops electrodes with reduced impedance, which provides better signal transmission.
Reduced impedance minimizes the risk of nerve tissue damage with prolonged use of implants. This feature is critical for devices designed to be constantly worn by patients with chronic diseases.
Coherence Neuro takes on the task of translating laboratory developments into clinical practice. The company organizes tests of prototypes in real medical conditions to ensure that the technology meets the practical needs of healthcare.
It is proposed to use new implants for neuromodulation in migraine, restoration of functions after spinal injuries and in experimental therapy of pancreatic adenocarcinoma. A wide range of applications makes development a universal neurostimulation tool.[1]
Notes
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