Depo-Provera

History

2025: Increased likelihood of brain malignancies

In late May 2025, hundreds of women filed a class action lawsuit against pharmaceutical company Pfizer over its contraceptive drug Depo-Provera. It is claimed that this injectable contraceptive increases the likelihood of developing malignant brain formations.

In 2024, the scientific journal British Medical Journal published the results of a study suggesting that women who received Depo-Provera injections for a year or more have a 5.6-fold increase in the likelihood of meningioma. This is an intracranial tumor that develops in the meninges. The danger of formation lies in squeezing the nervous tissue, which disrupts its normal functioning.

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Фото: Freepik

In an interview with DrugWatch, one of the women involved in the class action lawsuit said that she decided to start using Depo-Provera after an unplanned pregnancy. After three years of using the drug, she began to experience severe headaches and months of uterine bleeding. After the examination, she was diagnosed with meningioma. Other patients who used Depo-Provera faced similar problems.

The lawsuit alleges that Pfizer and other companies that made Depo-Provera generics were aware of the link between injections and the likelihood of neoplasms, but did not properly warn consumers about it. A British medical expert, who wished to remain anonymous, said that about 200 women contacted his company, who feared that Depo-Provera injections caused them to develop meningioma or increased the risk of it. Lawyers representing the plaintiffs intend to seek compensation from Pfizer.^[1]

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