| Developers: | National Cancer Research Center (CNIO) |
| Date of the premiere of the system: | October 2023 |
| Branches: | Pharmaceuticals, Medicine, Healthcare |
2023: Creating a Biobank
On October 31, 2023, it became known about the existence in Spain of the world's first biobank of living samples of human brain tissue. Samples collected from patients with metastatic brain cancer.
The study of brain tumors and the search for treatment for them usually begins with the study of animals, and only after any breakthrough on animal material do scientists need to look for living human material, and this is quite difficult - they have to cooperate with other institutions, work according to their legal and ethical rules. A biobank created by scientists at the National Cancer Research Center (CNIO) is designed to solve this problem.
In Spain, there is a whole network of collaborating organizations dealing with cancer and brain metastases. The network is called RENACER. When a person with brain metastases ends up in one of the institutions of the network, they can donate a tiny piece of their brain to a biobank.
Brain cells continue to be kept alive, so new drugs and the body's response to them can be tested on them. The process of maintaining cells in a "living" state is not so simple - after isolation from the patient's body, the tissue is placed in a container in which a temperature of 4 to 8 degrees is created. The container must enter the research facility in less than 24 hours or the tissue will die.
Storing such data can lead to the creation of a "digital avatar" of the patient, from which it will be possible to calculate the most suitable and effective treatment for the patient.
 | We have already signed several scientific contracts and plan to investigate organotypic cultures outside the patient's body in order to be able to create biomarkers of sensitivity or immunity to certain types of drugs - commented the authors of the study, scientists Manuel Vallente and Eva Ortega-Payno. |  |
In addition, scientists are investigating biobank samples and have already deduced about 150 different types of metastases. They share this information with the world cancer community.[1]
Notes
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