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2024/10/23 16:27:00

Brain cancer

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Cancer (cancer)

Main article: Cancer (cancer)

MRI brain tumour

2024

The creator of the online library "Filibust" died of brain cancer

Stiver, the creator of the Filibust pirate library, passed away. This became known on October 22, 2024.

In September 2024, Stiver said that he was diagnosed with an aggressive form of a brain tumor.

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I'm in the hospital with indecent size glioblastoma. Unfortunately, Filibust apparently ended there, like myself. Thank you all, it was fun, "he wrote.
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Stiver later clarified that the platform will continue its work. The owners of Filibusta confirmed that the creator of the library died in Germany.

Russian scientists have learned to manage the properties of substances that can become the basis of drugs against a brain tumor

Scientists at NRNU MEPhI as part of an international scientific team have learned to manage the properties of pyridoquinazolines - substances that can become the basis of drugs against a brain tumor. The university announced this on March 13, 2024. Read more here.

2023

The world's first biobank of living human brain samples has been opened

On October 31, 2023, it became known about the existence in Spain of the world's first biobank of living samples of human brain tissue. Samples collected from patients with metastatic brain cancer. Read more here.

A micro-device has been developed to select the optimal treatment for glioma

On September 6, 2023, American researchers at Brigham And Women's Hospital announced the development of a micro-device that will help doctors choose the optimal method of treating glioma, a malignant formation that affects the glial cells of the brain or spinal cord.

Glioma is the most common primary brain tumor. Every year in the United States alone, this type of cancer is diagnosed in about 20 thousand people. One obstacle in using targeted glioma therapy is that it is difficult to test many different drug combinations in a short period of time. The new development is designed to solve this problem.

Microdevice for glioma

The rice grain-sized device is implanted into the neoplasm and releases small doses of various drug formulations - up to 20 combinations of substances - for two to three hours. The microdevice is then surgically removed and surrounding tumor tissues are sent to the laboratory for analysis. The proposed method, as the authors of the project say, provides an unprecedented opportunity to assess the impact of various drugs on the environment of a malignant formation - that is, on cells that can make up almost half the mass of the entire tumor.

As of early September 2023, the device has been tested on six patients who have undergone brain surgery to remove glioma. Negative side effects from the use of the implant are not recorded. At the same time, the researchers were able to collect valuable biological data - in particular, on how the reaction changes depending on the concentration of the drug and what molecular changes a certain composition causes in cells. In the future, it is planned to implement the device through a minimally invasive procedure 72 hours before the main operation.[1]

Scientists have made a quantum leap in the treatment of a brain tumor

Researchers have discovered a new way to kill cancer cells in hard-to-treat brain tumors. This was announced on September 14, 2023 by the University of Nottingham.

A team of researchers, led by the Faculty of Pharmacy, has discovered a new way to use the unique properties of bio-nanoantennes - gold nanoparticles coated with special molecules. When used correctly, they can cause programmable cell death. The research results were published in the journal Nature Nanotechnology.

Researchers discover new way to kill cancer cells in hard-to-treat brain tumors

Xenografts based on tumor material of patients, in particular glioblastoma cells, were used as material for experiments. The survival rate of patients with this type of cancer is only 6.8%, and the average life after diagnosis is 8 months.

Bio-nanoantennes were able to attack cancer cells and still leave healthy cells unharmed. This result could potentially lead to a new method of surgical treatment of the tumor.

Scientists believe that the use of bio-nanoantennes can be called the first type of "quantum therapy."

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Our team showed that cancer cells obey the complex dance of electrons organized by the alluring world of quantum biology. With the advent of bio-nanoantennes, the world of quantum therapy has become more real. If quantum biological electrons are modulated accurately, these magnificent nanoparticles create a symphony of electrical signals that act on the self-destruction mechanism in cancer cells, stated Dr. Frenkie Rawson, head of the research team.
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Researchers have already found the first funds and applied for a patent in order to move on to full-fledged clinical trials. The use of bio-nanoantennes in humans requires more research to ensure the safety and efficacy of the treatment.[2]

A neural network has been created that defines the subtype of cancer during the removal of a brain tumor

On July 7, 2023, American researchers from Harvard Medical School announced the development of a new technology based on artificial intelligence, which provides the ability to determine the subtype of cancer during the removal of a brain tumor. Read more here.

Biodegradable ultrasound implant that helps chemo target brain to treat cancer created

On June 13, 2023, US researchers from the University of Connecticut reported on the development of a special ultrasound implant that helps chemotherapy affect the brain during the treatment of malignancies. Read more here.

Brain implant for cancer and Alzheimer's out

On June 27, 2023, French company Carthera announced the SonoCloud therapeutic ultrasound device, a specialized implant designed to treat cancer and Alzheimer's disease. Read more here.

Immunotherapy that suppresses the most aggressive type of brain cancer developed

On May 12, 2023, a group of researchers from Uppsala University in Sweden announced the development of a new method to combat glioblastoma - an aggressive brain tumor.

Experts emphasize that there is no effective way to treat this malignant. formations This is partly due to the tumor's ability to suppress or evade the body's natural immune response. In addition, the penetration of drugs into the brain is hindered by the blood-brain barrier, which serves as a highly selective filter.

Immunotherapy designed to suppress aggressive brain cancer

A new immunotherapy method aimed at treating glioblastoma relies on the use of so-called killer T cells. In brain cancer, blood vessels do not function normally, preventing these cells from entering the tumor. To solve the problem, the researchers used a viral vector that affects the blood vessels of the brain in such a way that they begin to produce a specific factor called LIGHT. As a result, it was possible to transport killer T cells from the blood to the tumor tissue. In addition, the proposed approach creates a favorable environment around blood vessels for therapy.

The researchers also found that their technology contributes to the formation of tertiary lymphoid structures: they are found in neoplasms, where they generate local and systemic antitumor reactions. The results suggest that the new immunotherapy improves the survival rate of patients with glioblastoma.

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The viral vector needs further development before we can start clinical research, but the results are very promising, "said Professor Magnus Essand, one of the authors of the work.[3]
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Russian scientists have developed a drug for diagnosing brain tumors with 100% accuracy

A drug based on DNA aptamers (short nucleotide sequences) developed by scientists from the Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky (KrasGMU) and the Federal Research Center "Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences" (FIC KSC SB RAS) with the participation of specialists from the Hospital of Medical Care and the Cancer Center (Krasnoyarsk), allows you to diagnose glial tumors with very high accuracy - the most common and aggressive type of brain cancer . This was announced on April 19, 2023 in the RSK group of companies. Read more here.

Nanowire designed to detect brain tumours in urine

In early February 2023, Japanese researchers from the University of Nagoya announced the development of a new technique that allows the detection of malignant brain tumors based on the results of urinalysis.

One of the signs that a person may develop a brain tumor is the presence of extracellular vesicles in the urine associated with malignant formation. These are tiny extracellular vesicles that are released by tissues or organs into their environment. Since certain types of RNA and membrane proteins are present in patients with brain cancer, they can be used to detect a tumor and determine the stage of its progression.

The presence of a brain tumor can be determined by the presence of extracellular vesicles in the urine

Specialists often detect brain tumors only after the appearance of neurological symptoms, such as loss of movement or speech, when the formation reaches significant sizes. The new method makes it possible to identify cancer at an early stage, which increases the likelihood of successful treatment.

To track extracellular vesicles in urine, Japanese scientists propose using a special device containing nanowires made of zinc oxide. In the process of analysis, extracellular vesicles "stick" to nanowires due to their surface charge and act as a biomarker to determine the presence of a brain tumor. Moreover, this method is suitable for detecting malignancies of any size and at any stage.

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A liquid biopsy can be performed using different body fluids, but blood tests are invasive. Urine research is an effective, simple and painless method that can be used to detect various diseases, including brain tumors, "said Takao Yasui, one of the authors of the project.[4]
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2022

Increased risk of brain tumor due to CT

On December 6, 2022, CT scans used for high-precision diagnostics may increase the risk of brain tumors, according to a study published in Lancet Oncology. Irradiation in increases the risk of brain cancer in children up to five times depending on the level of irradiation. Read more here.

Infrared implant developed to treat brain cancer

On October 13, 2022, it was reported that researchers at Stanford Medical University had developed and tested a wireless device to treat brain cancer.

Brain tumors are among the most deadly and intractable cancers. Glioblastoma, a particularly aggressive form, kills more than 10,000 Americans a year, and the average survival time is less than 15 months.

Implant developed to treat brain cancer

For patients with brain tumors, treatment usually involves surgery on an open skull to remove as much of the tumor as possible, followed by chemotherapy or radiation that comes with serious side effects and numerous hospital visits.

A new study by Stanford scientists has developed a less invasive treatment for brain tumors that, in trials in mice with brain tumors, significantly increased their survival time. This required only 15 minutes of treatment a day for 15 days, with the mice engaged in their usual activities.

The method is based on a new way to fight various types of cancer, involving the introduction of nanoparticles into the tumor, and then their heating. Exposure can occur through an electromagnetic field, ultrasound or light, and because cancer cells are more sensitive to heat than healthy cells, it allows them to be killed with minimal damage to surrounding tissues.

Developed by Stanford University, the device implants between the skin and skull and emits infrared light when turned on. Star-shaped gold nanoparticles are injected into a brain tumor through a tiny hole in the skull, and infrared light from the device heats them up to 5C. After several sessions of such treatment, the cancer cells were successfully destroyed.

The team says adjusting infrared power as well as the wavelength of light could allow them to target tumors of different sizes and locations in the brain.

The mouse trials also found that the treatment reduced the number of cancer cells in the brain and significantly increased the lifespan of the animals - on average three times that of untreated mice. When a course of chemotherapy was added to treatment, the mice lived even longer.

Researchers acknowledge that no matter how promising the study may seem, it is certainly difficult to extrapolate its results to humans. But experts hope to improve the device for use on patients, as another method to combat this deadly form of cancer.[5]

A new type of radiation therapy has begun to be applied, which significantly delays the recurrence of brain cancer

On September 19, 2022, UC San Diego Health, located in San Diego, United States, became the first academic health care system to offer new, narrowly targeted radiation therapy that delays cancer tumor growth and protects healthy tissue in brain cancer patients. Read more here.

2021: PET is the most effective tool to detect recurrent brain metastases

In early May 2021, a study was published in The Journal of Nuclear Medicine, the results of which say that positron emission tomography () PAT is the most effective tool for detecting metastases brain to and evaluating the effectiveness of modern treatments. When the results MRI of -monitoring are unclear, the addition of PET with 18F-FET helps physicians accurately diagnose recurrent brain metastases and reliably assess the patient's response to therapy. More. here

2020

GammaTile Announcement - Brain Radiotherapy Systems

In mid-December 2020, GT Medical Technologies released the GammaTile system, which can provide local radiation therapy to areas of the brain to remove the tumor. The purpose of this device is to reduce the risk of tumor recurrence and increase patient survival. Read more here.

Announcing 3D imaging technology that improves MRI brain tumor visibility

In late October 2020, researchers at Northwestern University in Chicago unveiled a new 3D imaging technique that improves brain tumor visibility on MRI scans.