| Developers: | NUST MISIS (National Research Technological University) |
| Branches: | Pharmaceuticals, Medicine, Healthcare |
2025: Obtaining a Patent
Scientists at MISIS University have patented a composite biocompatible microelectrode that can be used to electrically stimulate nervous tissue. It is applicable in the search for foci of epilepsy in the brain, stimulation of peripheral nerves to suppress phantom pain. It will also be useful in the study of spinal cord tissue regeneration. The university announced this on January 17, 2025.
Classical metal microelectrodes, due to their hardness and stiffness, can be highly displaced from the implantation area and do not have sufficient elasticity and flexibility. This leads to rejection and chronic inflammation. Subsequently, the electrode itself is damaged - cracked. Developed - much closer in mechanical properties to nervous and muscular tissues, which can reduce the body's response to its introduction. The composite material consists of polydimethylsiloxane with a content of conductive nano- and microparticles of carbon in various modifications (graphite, graphene, amorphous carbon). The electrode is used to point the current to the tissues.
 | To establish microelectrode biocompatibility, we conducted a cytotoxicity test. The material is harmless to human cells. During operation, the polymer conductive coating will take over part of the transmission of the electrical pulse, due to which the electrode will not fail. The characteristics may deteriorate, but the electrode will remain functional due to its flexibility: the total modulus of elasticity is less than the metal electrode. Thanks to this, when introduced into the body, the tissues surrounding the electrode will not be very irritated, - explained the engineer of the scientific project of the scientific and educational laboratory of tissue engineering and regenerative medicine NUST MISIS Sergei Zhirnov. |  |
Also, the development of scientists at NUST MISIS passed a dynamic tension test at a constant 37˚S temperature. The obtained value is constant and lies in the range characteristic of nervous tissue.
In the future, the electrode can be used as a functional part in domestic complexes for neurorehabilitation, cyber suits, complex exoskeletons for neurorehabilitation. The development will also be useful for researchers and doctors who use stimulation of the electrical activity of living tissues in their work.
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