Endometriosis

The disease is known from 70th years of the 19th century. Endometriosis origins are still not studied by scientists. Abnormal cells of endometrium extend on an organism together with blood and a lymph – in it the disease is similar to cancer. But, unlike oncology cases, the formed new nodes of endometriosis have good-quality character. Endometriosis can affect any bodies: from a uterus, ovaries, fallopian pipes and intestines to lungs, a conjunctiva of eyes and an internal cavity of a nose.

Spread of a disease

For 2018 with endometriosis every tenth woman in the world, or 187 million people aged from 15 up to 49 years is sick. By 2025 this number will grow by 5.3%, up to 196.6 million, said in the report of the British research agency Research and Markets. This disease is on the third place on prevalence of gynecologic pathologies. In every fifth case endometriosis is the reason of infertility.

In Russia, according to Rosstat, in 2016 such diagnosis was for the first time made to 155 of 100 thousand women while in 2015 of 100 thousand women, data for 2017 are specified, but, according to the experts, do not exceed last year's indicators. Nevertheless many researchers consider that it is more real cases of endometriosis. The disease often proceeds in the latent form and is difficult diagnosed. So, in Europe from the moment of identification of the first symptoms to the diagnosis "endometriosis" passes 6-7 years, and in Russia – 12 years.

Influence on mentality

Endometriosis destroys mentality of women stronger than HIV and cancer. The Australian scientists from Monash University in Melbourne as a result of a research of influence of endometriosis on life of women came to such conclusions. During the poll of 500 respondents researchers found out that 86.5% from them have depression symptoms, and detected a disturbing status in 87.5% of women. The strongest demotivating factors having negative effect on psychological state of women are impossibility to control a course of disease, the most severe pains and an inadequate status during attacks. Because of it at patients the social and personal activity decreases, the disease deprives of them optimism and confidence in the future.

Endometriosis very strongly influences everyday life of women, according to the report of scientists, published the other day in the Health Care for Women International magazine. The greatest discomfort causes pain – the polled women gave this indicator marks in the range from 40 to 50 points. Also psychological state is affected by not controllability of attacks of disease and its current – 40-60 points, negative emotions and experiences (40-47 points), lack of social support (39-50 points). Such indicator as falling of a self-assessment because of the inability "fit" into the commonly accepted behavioural framework in society and sharp "failures" in career and professional plans, got from 36 to 43 points. These results show that influence of endometriosis on life of women has more destructive impact, than such diagnoses as HIV or cancer, researchers from Melbourne note.

Endometriosis has the greatest impact on young women at the age of 18-25 years, the Australian scientists note. At this time in life of the woman there are many various changes and the foundation of the safe future is laid. Endometriosis deprives of them an opportunity to enter the personal relations, to plan family and children. According to the research ESHRE (European Society of Human Reproduction and Embryology), 75.4% of the polled women sick with endometriosis, periodically feel depressions or the strong concern connected with difficulties in partner and intimate relations.

Treatment

For 2018 there is no uniform technique of treatment of endometriosis: in each case the scheme is selected. The combined therapy including surgical intervention with the subsequent drug treatment is most effective. Completely it is impossible to cure a disease. In 21% of cases a recurrence takes place in 1-2 years after transaction, in 47% of cases – in 5 years, and in 57% of cases – in 7 years.

The greatest part of expenses on treatment lays down on the patient. Within the state budget only 780 million rubles to the aid of patients with endometriosis are selected, and patients spend about 50 billion rubles a year for drugs independently. According to the report of DSM Group company, the average cost of packaging of medicines for treatment of urogenital diseases in 2016 was 550 rubles.

"The main problem of therapy of endometriosis – duration. To save reproductive function and to minimize risks of a recurrence, patients should take medicine for months, and even years. Here very important point is the optimal selection of therapy allowing to suppress as much as possible growth of the centers of endometriosis and to recover reproductive function of the woman, – tell in pharmaceutical company "Nativa". – Now more agonists a hormone gonadotrophin-rileasing meet these requirements. They quickly remove a pain syndrome, reduce the endometrioidny centers, a recurrence warns and helps to recover fertility of the woman".

Such medicines are produced many pharmaceutical companies including the Russian producer "Nativa", comment in the company.

From medicines — agonists a hormone gonadotrophin-rileasing in Russia the medicines "Buserelin-long" and "Triptorelin-long" are produced. According to researches of pharmaceutical company "Nativa", purpose of this active ingredient in the postoperative period at common forms of genital endometriosis reduces a pain syndrome at 84% of patients, significantly reduces morbidity of periods and unpleasant feelings at bimanualny inspection, the probability of approach of spontaneous pregnancy at the same time significantly increases.