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2023: People began to get their vision back with stem cells
On August 18, 2023, American researchers from the specialized clinic Mass Eye and Ear announced the development of a new technology that allows the return of vision using transplants based on limbal stem cells. Read more here.
2021: Tinkov Foundation creates a stem cell register to save cancer patients
August 5, 2021 on the creation of a stem cell register to help cancer patients. The project is being implemented by the Tinkov Family Foundation, as banker Oleg Tinkov announced on his Instagram page. Read more here.
2017: First surgery to persade reprogrammed stem cells from a donor
On March 28, 2017, Japanese doctors applied an innovative technique for the treatment of macular degeneration, a disease associated with macular involvement in the retina, leading to blindness. A patient from Japan over 60 years old, suffering from this disease, was the first in the world to receive reprogrammed donor stem cells. If the new method is effective, doctors will be able to fight age-related macular degeneration, one of the most common causes of blindness in people over 55, Futurism reports.[1]
Macular degeneration occurs in macular degeneration, the central zone of the retina responsible for central vision. Until now, treatments for the disease have not existed, but the use of stem cells can make a difference.
An elderly Japanese with age-related macular degeneration was transplanted with induced pluripotent stem (iPS) cells. They were derived from mature donor cells that were reprogrammed into an embryonic state and then stimulated to develop a specific type of cell needed to treat, in this case retinal cells. Doctors hope that the method will stop the development of the disease and prevent blindness.
It is noted that the operation was successful, but the final conclusions about the effectiveness of the therapy can be made after all five planned iPS cell transplantation procedures.
Earlier, in September 2014, a similar method of treatment was used in the medical center of the Japanese city of Kobe. In that case, the woman was transplanted with retinal cells derived from iPS cells taken from her own skin. However, genetic abnormalities were found in the cells of the second patient, prepared similarly, and they were not transplanted. Doctors believe that genetic defects can accumulate in the cells of elderly people with macular degeneration, which increases the risk of the procedure. As for the woman who underwent the operation, a year after the treatment, her vision did not deteriorate, as one would expect with her disease.
The difference between the new method is the use of iPS cells. obtained from donor skin cells reprogrammed and stored in a special jar. It is formed to reduce the risk of rejection and allows patients to select the most suitable biomaterial for them. The Japanese Ministry of Health approved the study and planned a trial treatment for four more patients with macular degeneration.[2]
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