Ubikvilin-4

2019: The Israeli scientists detected unique protein ubikvilin-4

In Israel researches on genetic studying of cancer tumors based on medical faculty of Tel Aviv University were conducted. Scientific departments of molecular genetics of the person and biochemistry of Tel Aviv University detected unique protein on which level it is possible to judge weight of an oncological disease. The research was executed under the leadership of professor Yosef Shiloh and announced his results at the beginning of 2019.

Marker.ru of danger

Methods of treatment of a cancer tumor depend on degree of its malignancy: for destruction of some new growths surgery suffices, others demand chemotherapy and radiation, the third react only to immune therapy. The Israeli researchers found out that degree of aggression of a tumor is connected with the level of special protein – ubikvilina-4.

Our DNA is extraordinary vulnerable for external influences. Everything can constitute danger to it – from chemicals in air which we breathe, to food which we eat. All this can cause genetic disorders and different diseases, including cancer. However our immune system developed the difficult mechanism allowing to recover DNA. A part of this mechanism also is ubikvilin-4.

The Israeli scientists established that level ubikvilina-4 in a cancer tumor demonstrates its aggression: than it is more in a tumor of this protein, cancer is more aggressive there.

New step in the personalized therapy of cancer

The future of oncology is the personalized therapy of cancer at which the scheme of treatment is selected individually for a specific tumor. Will play an important role in development of such treatment ubikvilin-4.

"The new biomarker will provide us the important information on a stage and aggression of a disease and also on chances of the patient of treatment, - professor Yosef Shiloh, the head of a research says. – Tumors with the high level ubikvilina-4 can be steady against influence of radiotheraphy and some himiopreparata. However they can react to other types of oncological treatment better. It is obvious that this information is extraordinary important for doctors and patients".

It is expected that in the next years on the basis of the invention of the Israeli scientists new methods of diagnosis of cancer will be developed. Implementation of these methods is looked forward by oncologists of oncology centers of the country.