CTIBiotech

Founded in 2008, CTIBiotech specializes in biotechnologies, in particular, researches of cancer, stem cells, fabric engineering and in production of the innovation cellular models (in vitro and ex vivo) for biomedical, pharmaceutical and dermato-cosmetic researches and also medical devices used in cellular therapy.

CTIBiotech uses multi-disciplinary strategy which encourages and stimulates innovations in such adjacent areas as cellular biology, genetics, chemistry of biomaterials, engineering, nanotechnologies, biovisualization, biophysics and bioethics.

For 2018 CTIBiotech – the active member of professional and industrial associations, among which:

• Lyonbiopôle, competitiveness cluster;
• AFSSI (Association Française des Sociétés de Services et d’Innovation pour les Sciences de la Vie), the French association of service and innovative companies in the field of biology;
• The European center of a dermokosmetologiya which advances activity of the cosmetic companies from the region Rhone-Alps at national and international level.

2018: The first results of use of technology of 3D models of human sebaceous glands for skin care products

In March, 2018 BASF and CTIBiotech announce the first results of use of technology of 3D models of human sebaceous glands for skin care products. Experts showed production of a physiological sebum out of an organism in three-dimensional model of sebaceous glands of the person and methods of his regulation using active ingredients.

Sebaceous glands help skin to remain humidified and protect it from influence of external factors, such as severe weather, environmental pollution and microbic attacks. Sebum – a secret which is selected by these microscopic ekzokrinny glands greases and mitigates skin and hair.

On the cosmetic congress NYSCC BASF Care Creations and research institute of cellular therapy CTIBiotech provided the first results of joint survey of 3D models of fabric for development and testing of bioactive agents on care of skin. After two years of researches experts showed as production of a physiological secretion of sebaceous glands out of an organism in the long-term culture of three-dimensional model of a human sebaceous gland, and regulation of a secret using active ingredients.

Thanks to use of the technology of three-dimensional models of human sebaceous glands developed by CTIBiotech scientific it was succeeded to improve a portfolio of three-dimensional models of skin of BASF. New 3D - the technology provides researchers of care products for skin, persons interested to study function of sebaceous glands regarding age, microbic and inflammatory skin changes, the powerful platform.

"Work with BASF allowed us to check for short term in operation strong technology for researches on care of skin, – doctor Nicko Forraz, the CEO of CTIBiotech comments. – It positions CTIBiotech as world leader in the field of the innovation and even revolutionary technologies for the biological cellular tests applied in the field of medical cosmetics to skin".

"In comparison with modern methods of a research in simulated conditions, 3D models developed by CTIBiotech allow to carry out the analysis in conditions, more approximate to human physiology and to metabolism in sebaceous glands, – doctor Sabina Paine, the project manager in BASF comments. – Thus their technology helps us to accelerate development of the innovation and reliable ingredients for the market of care products for skin. Our understanding of process of metabolism in sebaceous glands forms a basis for development and testing of the advanced cosmetic bioactive agents for application in the field of care of skin, in particular, of care of oily skin".

"Thanks to the experience and examination in development of solutions for the market of medical cosmetics on care of skin, BASF understands advantages of cooperation with experts in fabric engineering, – professor Colin Makgukin, the executive scientific director and the president of CTIBiotech adds. – The following evolution of model of sebaceous glands will be based on three-dimensional technology of bioprinting which will allow us to reproduce in vitro completely micro glands in model with the actual thickness of skin".