Diadem (ultrasound device for controlling chronic pain)

2024: Product Announcement

In late August 2024, engineers at the University of Utah developed the Diadem ultrasound instrument, which non-invasively stimulates deep parts of the brain to treat chronic pain.

In patients with chronic pain, the root of the problem often lies in the distortion of pain signals. The Diadem device through ultrasound allows you to directly regulate the activity of certain parts of the brain and interrupts the transmission of distorted signals, bringing relief after one treatment session.

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The study involved 20 patients with chronic pain, each undergoing two 40-minute sessions of Diadem ultrasound therapy or sham placebo stimulation. To correct pain syndrome, the researchers analyzed the patients' functional MRI results, identified the intended areas of exposure, and customized Diadem ultrasound emitters individually. Patients assessed pain intensity at day and week after sessions, and 60% of participants in the real-treatment experimental group reported clinically significant improvement.

We ourselves did not expect such a pronounced and quick effect after only one session, the researchers noted. - The rapid onset of action and the persistence of the improvement achieved are important characteristics that open up new possibilities for the use of this non-invasive treatment method in many patients who do not benefit from other types of therapy.

A team of researchers is already preparing for the third phase of clinical trials to provide evidence for the device's registration and subsequent release to the market. To do this, they will need to test the results of prior trials in a wider patient population.^[1]

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