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SigTuple: Blood hemoglobin measurement system

Product
Developers: SigTuple Technologies
Date of the premiere of the system: February 2021
Branches: Pharmaceuticals, medicine, healthcare

2021: Announcement SigTuple - blood hemoglobin measurement systems

At the end of February 2021, researchers from the Indian Institute of Science and SigTuple Technologies developed a method for inexpensively measuring hemoglobin levels in small-volume blood samples. The new technique combines microfluidic chip and microscope with AI technologies.

Blood hemoglobin levels are an important marker of health conditions and can be used to diagnose various conditions, including pulmonary fibrosis and anemia. Currently, instruments used to test blood samples for hemoglobin content typically also measure a variety of other parameters. However, this is bulky and expensive equipment, and relatively large blood samples are required for its operation.

SigTuple (Blood hemoglobin measurement system)

Researchers at the research institute believe that a special imaging-based hemoglobin analysis system can solve these problems.

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In this study, we show that a system originally designed for imaging purposes can be used to perform biochemical tests without any additional modifications to the hardware unit, the researchers note.
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The system consists of a microfluidic chip on which a small volume blood sample is placed. Hemoglobin reacts with sodium lauryl sulfate, and the chip is evaluated under a microscope with automatic AI analysis of images. The microscope uses a green LED to illuminate the sample, since the sodium lauryl sulfate-hemoglobin complex absorbs light at this wavelength.

Microfluidic chips are relatively inexpensive - at $0.136 per unit, including the necessary reagents. In addition, this technology can be used to measure other substances in the blood, including cholesterol, protein and glycosylated hemoglobin.[1]

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