| Developers: | Tomsk Polytechnic University (TPU) |
| Date of the premiere of the system: | Nov 2022 |
| Branches: | Pharmaceuticals, Medicine, Healthcare |
2022: Announcement
Tomsk Polytechnic University has developed a calculator to effectively evaluate individual dosimetric radiation therapy plans. This became known in November 2022.
The TCP/NTCP calculator allows calculation of the probability of local control of the tumor and the probability of complication in normal tissues. This will help determine the most effective treatment plan for different types of tumors individually for each patient.
By November 2022, the quality of dosimetric radiation therapy plans is assessed according to physical criteria. However, such estimates often do not allow for unambiguous decisions on the choice of optimal radiation plans.
The new software takes into account additional radiobiological parameters, which makes it possible to more accurately determine the effective mode of dose delivery to a specific type of tumor, taking into account its location (shape, volume and location relative to critical anatomical structures) and more accurately assess the expected biological effect. The program is a WEB application hosted on the server and available for use by specialists in the field of radiation therapy.
The calculator works as follows, says Yana Sutygina, engineer of the Technological Reference Center for Ionizing Radiation in Radiology, Radiation Therapy and Nuclear Medicine at TPU. The specialist uploads into the software a dataset describing tumor volume and absorbed dose distribution in the tumor and at-risk organs. Next, it prescribes the radiobiological parameters corresponding to this type of tumor and risk organ, as well as the dose setting mode. Based on these data, the system calculates the likelihood of complications and local control of the tumor. This makes it possible to provide a more accurate assessment of the effectiveness of a particular developed radiotherapy dosimetric plan for a particular case.[1]
Notes
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