Developers: | LENZ Therapeutics |
Date of the premiere of the system: | August 2025 |
Branches: | Pharmaceuticals, Medicine, Healthcare |
Content |
History
2025: Start of Sales
In August 2025, it became known about the entry into the market of VIZZ eye drops from LENZ Therapeutics. They temporarily restore close vision in patients with age-related long-range vision for up to 10 hours. The drug begins to act 30 minutes after use and exceeds the existing analogues in terms of duration of effect, which work from 4 to 6 hours.
The journey from concept to finished drug has taken 20 years of research and development. The ocular solution based on aceclidine functions according to the principle of contraction of the iris sphincter muscle, which creates the effect of obscura and increases the depth of focus of vision.
The mechanism of action of the drug is based on constriction of the pupil, which works similar to the aperture of the camera. The decrease in pupil diameter allows light to pass through the central part of the lens, where optical distortion is minimal, which temporarily compensates for age-related changes in eye accommodation.
Clinical trials of the safety and efficacy of VIZZ were conducted in two groups of volunteers. The first group included 466 participants who received the drug once a day for 42 days. The second group consisted of 217 people using drops daily for six months to assess long-term safety.
The preliminary cost of the drug will be approximately $100 per month, which is equivalent to ₽8 thousand at the current exchange rate. The manufacturer warns that insurance companies do not plan to include this drug in drugs covered by policies, which makes treatment completely paid for patients.[1]