The world's first bioprinting operation on a patient was carried out in Russia

2023: World's first bioprinting surgery on a patient

The Main Military Clinical Hospital named after Academician N.N. Burdenko carried out the world's first operation using a bioprinter consisting of a roboruka, a bioprinting system and computer vision. This was announced to the medical portal Zdrav.Expert on December 26, 2023 by representatives of the MISIS University.

source = NITU MISIS

The device was developed by scientists of NUST MISIS and pioneers of the Russian bioprinting, a company. 3D Bioprinting Solutions The feed trajectory in biopolymer situ, that is, immediately into the wound, is in place programmed by a university specialist after scanning the injury site. The doctor took the patient's cells from the bone marrow to "put" them into the bioprinter. The scan and bioprinting robot were carried out without human involvement. According to the center's doctors, this equipment opens up completely new opportunities for the treatment of complex soft tissue injuries.

source = NITU MISIS

"We see how bioprinting methods are beginning to be introduced into the clinic in different countries of the world, in Russia our company has been developing similar technologies for ten years. Nevertheless, in situ biopsy directly into a wound defect, carried out in the world for the first time. Of course, we are glad that Russia retains a country priority in the development of bioprinting, and the technology leaves the walls of laboratories to clinical institutions and begins to benefit real patients, "said Yousef Hesuani, managing partner of 3D Bioprinting Solutions.

source = NITU MISIS

The main difficulties for the surgeon during the operation: a difference in the height of the wound, bleeding, interfering with the spokes to fix the bones. But thanks to the developed wound scanning and printing system, a bioprinter under the supervision of a surgeon can accurately and quickly close the damage with polymer compositions with the cells of the patient himself.

source = NITU MISIS

"With a robotic hand, we printed a matrix in the forearm with biochernils to replace a soft tissue defect. The composition consists of a mixture of highly purified concentrated sterile collagen solution and cells. This technique was carried out for the first time, it is especially relevant for multiple fragmentation wounds of the limbs, when the donor resource is limited, "said traumatologist-orthopedist of the 1st qualification category, surgeon Vladimir Besedin, who controlled the operation at the N.N. Burdenko.

According to him, with extensive wounds in the future, it is planned to scan the body completely and replace all wounds with this method - this will speed up the time of their healing and reduce the time spent by patients in the hospital.

source = NITU MISIS

As noted for his part, Director of the Institute of Biomedical Engineering NUST MISIS Fedor Senatov, in the near future we can expect a larger introduction of bioprinting technology in situ into clinical practice.

"We have taken the first step into a future in which surgeons will not just manipulate robotic systems, but robots will be full autonomous participants in operations. The most important precedent has been created for the use of a bioprinter to heal large soft tissue injuries immediately on a patient without preliminary preparation of 3D models and without the need to implant tissue equivalents printed in advance, "Fedor Senatov summed up.