Biosensors

2025: Global Implantable Biosensors Market Size Reaches $2.67 Billion for the Year

In 2025, expenditures on the global market for implantable biosensors amounted to $2.67 billion. The lion's share of costs - more than 40% - fell on the North American region. Such data are provided in a Fortune Business Insights study, the results of which were published on March 5, 2026.

Implantable biosensors are high-tech devices implanted in tissues for continuous monitoring of various indicators, such as cardiac activity, glucose content, etc. Sensors can record levels of nitric oxide associated with cancer processes and inflammation. Many diseases, in particular, ailments affecting the heart and nervous system, cannot be identified during short visits to the hospital: biosensors are used to help diagnose them. Such sensors provide real-time data, allowing doctors to detect problems early and quickly adjust treatment.

One of the market drivers is the growth of patients with chronic diseases including diabetes and cardiovascular pathologies. According to the World Health Organization (WHO), from 1990 to 2022, the number of people living with diabetes increased from 200 million to 830 million people. During this period, the prevalence of the disease among those over 18 years old doubled - from 7% to 14%. Moreover, more than half (59%) of adults over 30 years of age with a diagnosis did not take drugs to control the disease. At the same time, cardiovascular diseases are the leading cause of mortality in the world - in 2022, about 19.8 million people died from such pathologies. Early diagnosis and regular medical observation of these diseases remain key tools for preventing severe consequences: implantable biosensors help to monitor patients.

Technological advances have a positive impact on the industry. Developers are constantly improving the characteristics of sensors, increasing their accuracy and service life, as well as reducing size. The integration of artificial intelligence provides an effective analysis of transmitted indicators, which contributes to timely treatment and expands opportunities in terms of personalized therapy. An increase in the proportion of older people requiring ongoing medical control is also driving increased demand for implantable biosensors. The use of such sensors reduces the number of repeated hospital visits, reduces the burden on healthcare systems and increases patient comfort.

Analysts segment the market into electrophysiological, piezoelectric, electrochemical sensors, etc. In 2025, the largest share of revenue was provided by the first type of products - 49.5%. The area of ​ ​ application is dominated by the direction of monitoring cardiac activity. From a geographical point of view, North America leads with 44.94%, or $1.2 billion. Major industry players on a global scale are:

• Abbott;
• Medtronic;
• Boston Scientific;
• Biotronik SE & Co. KG;
• Senseonics Holdings;
• Profusa;
• Endotronix;
• NeuroPace;
• Neuralink;
• Paradromics;
• Synchron.

In 2026, the volume of the market in question is expected to reach $2.87 billion. At the same time, the United States will account for $1.1 billion (approximately 38.2% of global spending), the Asia-Pacific region - $0.62 billion. Fortune Business Insights analysts believe that in the future, the CAGR will be 8.1%. As a result, by 2034, costs could increase to $5.36 billion.^[1]

2023: Discovered nanoparticle effect will enable biological sensors

An international team of physicists has shown that a certain shape allows nanoparticles to be in an electromagnetic sense larger than their geometric dimensions. This was announced on August 14, 2023 by representatives of the Moscow Institute of Physics and Technology. The discovered effect will help in the creation of biological sensors, materials for solar panels and elements of optical and quantum computers. Read more here.

2020

Start using biodegradable implants to measure nitrogen oxides

In mid-November 2020, researchers at the University of Pennsylvania developed an implantable sensor that can measure the levels of NO and NO2 gases in the body. The flexible sensor, which consists of silicone and magnesium, is completely biodegradable, so it does not need to be removed after implantation. Read more here.

Electronic sensors of temperature, oxygen in the blood and ECG began to be applied directly to the skin

In mid-October 2020, researchers from Pennsylvania State University and Harbin Institute of Technology in China developed a way to print electronic sensors directly on the skin without releasing excessive heat in the process. Thanks to this technique, doctors can receive high-quality recording of a number of vital signs, for example, temperature, blood oxygen content and ECG.

Biometric sensors usually work best when placed in close proximity to the body. While wearable devices such as wrist pulse oximeters are already commonplace these days, they can only be worn over some areas of the body and are often not too comfortable. Therefore, the researchers developed a new technique.

Electronic sensors of temperature, oxygen in the blood and ECG began to be applied directly to the skin

Bonding silver nanoparticles into flexible electronic components typically requires high temperature sintering at 300 degrees Celsius, which cannot be performed directly on the skin. The team of researchers decided to find a material that would lower the temperature required for sintering and developed a sintering paste layer of polyvinyl alcohol and calcium carbonate. This paste not only provides sintering of the nanoparticles at room temperature, but also makes the surface of the resulting material smooth and flexible, which allows the sensors to be applied directly to the body.

Researchers have already created sensors to assess blood oxygen, take ECGs, measure temperature and humidity. They also connected the sensors to a common network that can transmit real-time readings to a nearby monitor. The sensors can work for several days, and they can be removed easily under a hot shower. In this case, all devices can be reused or sent for recycling, since they are not damaged during the removal process.^[2]

MIPT found a way to raise the sensitivity of biosensors to a level sufficient for domestic use

On January 28, 2020, the MIPT reported that a way was found to raise the sensitivity of biological sensors to a level sufficient for their use in household appliances. The work was carried out by MIPT with the support of the Russian Science Foundation.

Biosensor is an electrochemical sensor that allows you to determine the composition of biological fluids in real time. The MIPT noted that the only mass household use of biosensors is devices for instant measurement of blood glucose levels. But futurologists promise that in the near future, household electronic devices that analyze the composition of sweat, saliva, eye fluid and other secretions using biosensors will be able to identify the person, make medical tests, make diagnoses, continuously monitor the state of health and make the optimal diet for a particular person depending on the current state of his body.

Until recently, their low sensitivity and unbearable cost for the consumer market did not allow them to seriously talk about such applications of biosensors. But it seems that a breakthrough is planned in this area: a group of scientists from Fiztech proposed a fundamentally different biosensor design, promising to increase its sensitivity and reduce cost. Both are many times over.

"A traditional biosensor consists of an annular resonator and a waveguide located in the same plane as the resonator. We decided to try to separate these two elements, place them in different planes, arrange the ring above the waveguide, " noted Kirill Voronin, author of the idea, master's student at MIPT and employee of the laboratory of nanoptics and plasmonic

Previously, none of the researchers tried to do this, because in laboratory conditions it is much easier to make a single-level flat structure: a thin film is applied to the substrate, etched out it and both the ring resonator and the waveguide are obtained at the same time. The two-tier design of the biosensor turned out to be more difficult to manufacture in single experimental copies, but cheaper in mass production at microelectronics plants, where all technological processes are focused on the layered placement of active elements.

But the main thing is that the proposed volumetric design of the biosensor makes it possible to achieve many times more sensitivity from it, according to the MIPT.

The work of biosensors is based on the fact that due to the absorption of organic molecules by the surface of the sensor, a slight change in the refractive index of the latter occurs. This change is captured by a resonator whose resonance conditions depend on the refractive index of the external medium. The resonance phenomenon has the property that even the weakest fluctuations in refractive index cause a significant displacement of the resonant peaks. Therefore, the biosensor is able to respond to almost every organic molecule that falls on the surface of the sensor.

"We have a strip waveguide located under the resonator, in the thickness of the dielectric. The resonator is located at the interface between the dielectric substrate and the external environment. This makes it possible to significantly increase its sensitivity by selecting the refractive indices of two media, " noted Alexey Arsenin, one of the co-authors of the work, leading researcher at the Laboratory of Nanoptics and Plasmonics MIPT

In the biosensor layout proposed by scientists, its entire optical part - the source and detector of radiation - is located inside the dielectric. Outside, only the sensitive zone of the structure remains - a golden ring with a diameter of several tens of micrometers and a thickness of several tens of nanometers.

Biosensor device. The waveguide is located inside the dielectric. The resonator in the form of an annular waveguide is located outside the substrate, on the border with the studied biological fluid. Changing its refractive index results in a resonance curve offset. Sensors

"Our scheme is designed to significantly simplify and reduce the cost of biosensors. For the production of sensors built on our principle, only optical lithography is enough. No moving parts are required, enough customizable laser working in a very narrow range, " noted Kirill Voronin, author of the idea, master's student at MIPT and employee of the laboratory of nanoptics and plasmonic

According to Valentin Volkova, director of the Center for Photonics and Two-Dimensional Materials at MIPT, it will take about three years to create an industrial model based on the proposed technology.

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