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2020/07/10 00:07:06

Melanoma

Melanoma is a malignant tumor that, most often under the influence of ultraviolet injury, develops from melanocytes - cells that produce dark skin pigment.

Content

Main article: Skin cancer

Prevention

In the southern regions, in the bright sun, the moles zone must be protected with sunscreen, because this is where melanoma occurs.

Importance of early diagnosis

Melanoma is a form of malignant neoplasms, which is characterized by aggressive metastasis, and therefore 40% of patients cannot be saved. At the same time, a standard skin examination during medical examination or preventive examination allows 90% of patients to be cured.

For timely detection of melanoma, early diagnosis is important in any formation on the skin. One of the main reasons for the development of the disease is excessive ultraviolet radiation. At risk are people with fair skin and the presence of a large number of pigment spots and moles (more than 50). Do not be in the sun at the peak of its activity - from 11 to 15 hours, you need to protect the skin with clothes, sunscreen and regularly undergo examination by specialists.

It is important to know what the mole looks like, which is dangerous and can lead to skin melanoma. A common mole is a pigment spot with uniform coloration, even and symmetrical contours.

If the mole began to change its circle, color, become asymmetrical, bleeding appears - these may be signs of melanoma. If such signs are detected in yourself, it is imperative to consult a specialist doctor, it is better to start with a dermatologist who, if a malignant neoplasm is suspected, will refer the patient to an oncologist. A significant part of the risk factors for malignancies is manageable and human health largely depends on the efforts made by him.

2024

With the help of gene editing technology CRISPR, it was possible to turn off genes that make drugs unable to treat melanoma

In mid-October 2024, scientists at the ChristianaCare Institute showed that CRISPR gene editing tools could be used to safely disable gene mutations associated with melanoma therapy resistance. CRISPR restores melanoma cell response to antitumor drugs, thereby helping patients with previously incurable disease. Read more here.

New Russian therapy can treat melanoma with 40% efficacy

Russian scientists presented the results of a study of a new drug for the treatment of resectable melanoma, which demonstrates an effectiveness of about 40%. This became known on October 1, 2024. Read more here.

New immunotherapy provides high 10-year survival in melanoma with metastases

At the end of September 2024, scientists published long-term data from an international study, according to which the new immunotherapy ensured a high 10-year survival rate for melanoma with metastases. About half of metastatic melanoma patients treated with a combination of immune checkpoint inhibitors lived without relapse for 10 years or more. Read more here

The Russian original drug for the treatment of melanoma is included in the list of VEDs

The Commission of the Ministry of Health included the original drug "Nurdati," developed by scientists of the biotechnological company BIOCAD, in the list of vital and essential drugs (VED). This solution opens up access to innovative therapies for more than 550 patients. Biocad announced this on August 23, 2024. Nurdati is a monoclonal antibody drug created to treat patients with melanoma, including cases with metastases. Read more here.

2022

A bandage has been created that kills melanoma and restores healthy cells

In mid-July 2022, a surgical bandage specifically designed to facilitate and enhance photothermal therapy following melanoma resection was unveiled at the University of Nottingham in the UK. The product allows to carry out photothermal therapy in the near infrared region, which lasts only 15 seconds, every 48 hours. The technology involves the destruction of all remaining melanoma cells, while stimulating the regeneration of healthy cells at the site of resection, the developers say. Read more here.

Service for detecting melanoma using a smartphone camera launched in Russia

On May 23, 2022, it became known about the work of the Russian online service for the early detection of melanoma. The platform is available in 30 constituent entities of the Russian Federation, and by the end of 2022 it will become available throughout the country, project developer Sergei Yakunin told TASS. Read more here.

2021

In the Rostov region, 269 patients with skin melanoma were identified

In the Rostov region in 2021, 1642 new cases of malignant skin neoplasms were detected, of which 269 were patients with skin melanoma.

Medsi has opened an international melanoma center

On May 27, 2021, the official opening of the International Melanoma Center took place. This is the Medsi project, which will combine the company's experience in the diagnosis and treatment of skin cancer. Read more here.

2020

The Russian Ministry of Health published standards of medical aid to patients with a melanoma

In July 2020, the Ministry of Health of Russia announced the standards of medical care for patients with melanoma. The document "On the approval of standards of medical care for adults in malignant neoplasms of the skin (melanoma of the skin and mucous membranes, Merkel carcinoma) immediately combines all standards for these nosologies and includes all types of diagnosis, treatment and dispensary observation.

Standards were approved for different stages of skin melanoma 0-I, IIA, IIB-C, III, IV, III-IVB, IIIC-IV, IVC mucosal melanoma and for progression of skin and mucosal melanoma 0-IV stages, as well as for Merkel carcinoma of different stages.

В июле 2020 года Ministry of Health of Russia published standards of medical care for patients with melanoma

According to Vademec, the document summarizes and updates the standards for these diseases, reflected in several orders at once. Current standards, for example, separately describe surgical treatment, drug, radiation and remote radiation therapy.

According to the deputy chief physician of the hospital of the Pirogov Center for Oncology Vladislav Sarzhevsky, the incidence of melanoma is growing in Russia.

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Official statistics: four to five cases per 100 thousand population. There are two main reasons here. Firstly, the awareness of the population is growing and the detection of the disease is growing. The second factor is changes in the culture and lifestyle of Russians, - said the specialist.
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Residents of the country, as the doctor noted, began to travel more often to southern countries where there is a lot of sun, and not everyone thinks that the skin should be protected from harmful ultraviolet radiation.

The chief oncologist of the Ministry of Health, academician of the Russian Academy of National Economy Kaprin says that a malignant formation on the skin - melanoma - can develop even in the absence of moles on the body.

In Moscow, in 2019, melanoma was included in the list of six diseases, for the immune and targeted therapy of which additional funding was allocated.[1]

Free diagnosis of melanoma in 10 thousand Russians will be held in 10 cities of Russia

On World Day Against, cancer February 4, 2002, the list of cities where free diagnosis of melanoma leather will be held became known. In 2020, it is planned to survey more than 10,000 Russians in ten cities:,, Russia,, Rostov-on-Don,, Nizhny Novgorod,, and Kazan Krasnoyarsk. Novosibirsk Krasnodar Orenburg Registration for Surgut Stavropol To Ufa those wishing to undergo screening will be carried out on the website живибезстраха.рф.

10 cities will host free diagnosis of skin melanoma 10 thousand Russians
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As a public opinion poll showed, many Russians actually do not know anything about the disease and what to do if it is discovered, "said Daria Belyakova, head of the corporate social responsibility and corporate culture department at Biocad. - A public opinion poll conducted by VTsIOM in 2019 showed that the majority of Russian citizens actually do not know anything about the disease. At the same time, skin melanoma is one of the most aggressive types of cancer, in which the time of diagnosis and the period of start of treatment play a decisive role. Despite the complexity of the disease, doctors have a wide range of therapeutic options in their arsenal: from targeted to immunotherapy. Modern drugs allow you to achieve long-term remission and translate tumor processes into chronic diseases - often even those that were previously considered incurable.
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From 5 to 7 people per 100 thousand of the population of Russia are sick with melanoma

According to the World Health Organization at the beginning of 2020, around 132,000 new cases of melanoma are diagnosed worldwide each year. According to the National Medical Research Center of Oncology named after Blokhin, melanoma in Russia is found in seven cases for every 100 thousand people, and this figure tends to increase.

The incidence of melanoma in Russia as of the beginning of 2020 is at an indicator of five to seven people per 100 thousand population. In a number of countries in the Western world, this figure is two to three times higher.

2019: Biocad presents clinical trial results for melanoma therapy drug Prolgolimab

On June 25, 2019, Biocad presented the results of clinical studies of the original drug for the therapy of melanoma. Read more here.

2017: Melanoma detected in 11.2 thousand people in Russia

According to the Ministry of Health of the Russian Federation, in 2017, melanoma was detected in 11.2 thousand people in Russia.

See also