Roman Safronov worked in the Ministry of Health from 2010 to 2014, took a position of the deputy director of IT department since 2012. In the ministry he was responsible for development of the Single state information system of health care and other information systems of the Ministry of Health.
In 2015-2016 - worked in Federal Agency for Ethnic Affairs and was responsible for creation of a monitoring system of the international conflicts (cm of an interview of TAdviser of August, 2016).
In 2017 headed "National Center of Electronic Models" company.