| Developers: | The pennsylvanian university - University of Pennsylvania |
| Date of the premiere of the system: | November, 2020. |
| Branches: | Pharmaceutics, medicine, health care |
2020: Start of use of biodegradable implants for measurement of nitrogen oxides
In the middle of November, 2020 researchers from the Pennsylvanian university developed the implanted sensor which can measure levels of NO and NO2 gases in an organism. The flexible sensor consisting of silicone and magnesium is completely biodegradable therefore it does not need to be removed after implantation.
Measurement of the NO and NO2 levels in an organism can provide to doctors very useful information. NO participates in expansion of vessels, and its dysfunction plays an important role in development of cardiovascular diseases whereas NO2 is toxic impurity which can lead to progressing of the chronic obstructive pulmonary disease (COPD). At the same time reactive NO can turn into NO2 at contact with oxygen.
Modern technologies of measurement of such gases are not optimal - bulky wearable sensors can not always provide physiologically significant indications. Use of the implanted sensor will allow to receive more exact indications from within a body, but requires two transactions - one for implantation of the sensor, and another - for its removal. These problems inspired researchers from the Pennsylvanian university on development of the implanted biodegradable sensor.
The developed sensor consists of the silicon sensitive to NO, and the components of magnesium installing electrical equipment.
 | Silicon is unique - it is construction superstable material of modern electronics, - one of researchers explained. - Besides, silicon is biodegradable. It is very slowly dissolved, approximately from one to two nanometers a day, depending on the environment. |  |
Researchers already tested in the vitro device and showed that the device is capable to estimate quantitatively gases and slowly collapses eventually. According to experts, the solution ours application in clinical practice in the USA. They added that, perhaps, once this technology can be used for measurement of other medical parameters without the need for the subsequent removal of the sensor.[1]
Notes
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