Enteromix (cancer vaccine)

Cancer vaccines

Main article: Cancer vaccines

History

2024: Start of Vaccine Use

In Russia, the selection of patients for participation in the first phase of clinical trials of the oncolytic vaccine Enteromix, developed by the National Medical Research Center of Radiology of the Ministry of Health together with the Engelhardt Institute of Molecular Biology, has begun. This was announced by the chief freelance oncologist of the Ministry of Health Andrei Kaprin on December 17, 2024.

According to Rossiyskaya Gazeta, the vaccine has successfully passed all preclinical tests that have lasted several years. The drug is based on four non-pathogenic viruses that can destroy malignant cells and activate the patient's antitumor immunity.

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Freepik

I am glad to announce the beginning of prescreening aimed at selecting patients for participation in the first phase of a clinical trial of an oncolytic vaccine, "said Andrei Kaprin, chief freelance oncologist of the Ministry of Health.

Patients aged 18 to 75 years who have previously received antitumor therapy, which turned out to be ineffective, will be allowed to participate in the trials. In this case, the general health of candidates should allow additional treatment.

According to the developers, the effectiveness of the drug can range from slowing the growth of the tumor to its complete destruction. The mechanism of action of the vaccine is based on the ability of viruses to purposefully attack cancer cells.

The tests are carried out within the framework of the state program for the development of innovative methods of treating cancer. The vaccine is a completely domestic development.

Clinical studies will take place in stages with careful monitoring of the condition of the participants. Each step involves an assessment of the safety and efficacy of the drug in a specific group of patients.

In case of successful passage of all phases of clinical trials, Enteromix may become the first Russian oncolytic vaccine admitted to widespread use in medical practice.^[1]

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