Psoriasis

Psoriasis is a chronic, noninfectious, recurrent disease with predominant skin involvement. The disease manifests itself with itching and the formation of red rashes, papules - nodules that rise above the surface of the skin. Papules merge into plaques, which are covered with silvery scales and strongly peeling. In recent years, psoriasis has been spreading among 16 to 22-year-olds. Experts associate this fact with hormonal changes^[1]

Among chronic skin diseases, psoriasis occupies a leading ^[2] They are sick with about 3% of Russians^[3] to the high risk of developing several immunoinflammatory diseases in one patient, early diagnosis and adequate therapy are extremely relevant. According to various authors, 30% of patients with psoriasis are diagnosed with psoriatic ^[4]

Psoriatic arthritis (PsA) is a chronic inflammatory disease with a wide range of clinical manifestations. In psoriatic arthritis, not only the joints, spine and tendons are involved in the inflammatory process, but also the nail plates, intestines and organs of vision. PsA is a potentially disabling disease.

Thus, a patient with psoriatic arthritis is monitored by two specialists - a dermatologist and a rheumatologist. For greater treatment effectiveness, consultations with doctors of two profiles are necessary.

Possible complications

Psoriatic arthritis (PsA)

Main article: Psoriatic arthritis

Almost every patient, after the expiration of time, with ineffective therapy for psoriasis, can receive a complication of psoriatic arthritis, which, in turn, in the absence of effective treatment, is highly likely to invalidate patients. One in five patients may have such complications.

Social stigmatization

Another problem of patients suffering from psoriasis and is psoriatic arthritis social stigmatization (from Greek στíγμα - "label, stigma"). Due to the low awareness of society about the non-communicable nature of the disease and the peculiarities of its course, patients may feel very uncomfortable. Often, against this background, patients with psoriasis develop a depressive state: up to 7% of people with psoriasis may be prone to. to suicide

Disability

In the Russian Federation, according to information on disability due to psoriasis, 11,311 people (both adults and children) were registered among the adult and child population in the 01.12.2021.

Patients with psoriasis have the right to establish disability in accordance with Order of the Ministry of Labor and Social Development of the Russian Federation dated 27.08.2019 No. 585n.

Chronicle

In the world

2022: Takeda acquires Nimbus Therapeutics for $6 billion

On December 13, 2022, Takeda entered into an agreement to acquire the allosteric tyrosine kinase 2 (TYK2) inhibitor Nimbus Therapeutics for $6 billion, NDI-034858. Oral therapy is used to treat a variety of autoimmune diseases. Read more here.

In Russia

2022: First case of psoriasis cure with stem cell therapy recorded

On October 21, 2022, a South Korean stem cell research company, Miracell, announced the creation of a new regenerative skin stem cell therapy using the Smart Emcell2 system. Read more here.

2021: Nearly 40% of patients with severe psoriasis failed inpatient treatment

According to a study by the interregional charitable public organization "Skin and Allergic Diseases," almost half of the respondents (48%) with skin diseases were unable to get to a specialized doctor and 39% were unable to undergo treatment in a hospital during a pandemic. Over 60% of patients diagnosed with severe, recurrent common psoriasis do not know that they can get a disability, and with it medical care with the use of modern therapy. This was announced on December 6, 2021 by representatives of the organization "Skin and Allergic Diseases."

The majority (93.8%) of patients with severe and moderate psoriasis stated that the treating physician did not refer them for a medical and social examination to consider the issue of attribution of disability due to psoriasis and/or psoriatic arthritis.

"We see that psoriasis is one of the most common diseases related to autoimmune or immunoinflammatory diseases. Almost every patient, after the expiration of time, with ineffective therapy for psoriasis, can receive a complication of psoriatic arthritis, which, in turn, in the absence of effective treatment, is highly likely to invalidate patients. One in five patients may have such complications. If we analyze the spending of the state that it incurs on the treatment of patients, we can see that the indirect costs associated with the disease are among the largest. Indirect losses are formed from the state's costs of disability payments, temporary disability, mortality, "said Ruslan Dreval, director of the Center for Social Economics.

Patients with psoriasis have the right to establish disability in accordance with Order of the Ministry of Labor and Social Development of the Russian Federation dated 27.08.2019 No. 585n. According to Olesya Mishina, head of the public organization "Skin and Allergic Diseases," the regulatory regulation of the processes for establishing and extending the status of "disabled" for patients with psoriasis and psoriatic arthritis, valid for December 2021, does not fully reflect the characteristics of therapy and the course of this disease in accordance with existing practice and clinical recommendations, which leads to restrictions on the rights of citizens to receive the necessary social assistance.

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