Renal denervation

2023: European Community of Cardiology recommends kidney denervation to treat blood pressure

At the end of February 2023, it became known that patients whose high blood pressure remains despite taking drugs and changing their lifestyle can be treated with renal denervation. The relevant recommendation was made by the European Community of Cardiology. Read more here.

2018: Renervation method used for the first time in Russia

For the first time in Russia, the Research Institute of Cardiology of the Tomsk Research Institute of Medical Sciences performed operations to treat hypertension by renervation using the innovative Symplicity Spyral catheter developed by Medtronic. This was reported on July 6, 2018 in Medtronic Russia. Read more here.

2017: Medtronic study

In late August 2017, Medtronic presented the results of the company-sponsored SPYRAL HTN-OFF MED study on the efficacy of renal (renal) denervation.

The kidneys play a key role in regulating blood pressure (BP). Blood pressure lowering medications affect renal mechanisms to varying degrees. But in some cases, even a combination of three to four drugs with a different mechanism of action does not allow achieving normalization of blood pressure. 

Medtronic study finds kidney denervation reduces blood pressure

In the SPYRAL HTN-OFF MED report published at the annual congress of the European Society of Cardiology (ESC; Barcelona, August 26-30, 2017), states that renervation contributes to lower blood pressure in patients with uncontrolled hypertension.

The patients who took part in the testing were randomly divided into groups, one of which underwent renervation of the main renal arteries and their branches, the second - placebo. Researchers measured BP at baseline and for three months, then compared rates in each patient group.

At ESC 2017, the three-month results of the first 80 patients were presented, of which 38 people underwent renervation, 42 patients received placebo.

In patients who underwent renal denervation, systolic and diastolic BP decreased by 10.0 mm Hg and 5.3 mm Hg, respectively, compared with a decrease of 2.3 mm Hg and 0.3 mm Hg in the control group.

The data of daily outpatient monitoring of systolic and diastolic BP decreased by 5.5 mm Hg and 4.8 mm Hg, respectively, in the group of patients after denervation, while in the placebo group the indicators decreased by 0.5 mm Hg and 0.4 mm Hg. Art. respectively.^[1]

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